Figure 1 showed an integration of these three cellular levels of our FEM avascular
tumor growth model. In the beginning, there is a parameter initialization step which
includes: (1) an initialization of diffusion coefficients, initial concentrations,
concentration thresholds, and metabolic rates of nutrients and GIF for their
tumor growth model. In the beginning, there is a parameter initialization step which
includes: (1) an initialization of diffusion coefficients, initial concentrations,
concentration thresholds, and metabolic rates of nutrients and GIF for their
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